Do you know what Tardive Dyskinesia is?

FDA Approves Treatment for Tardive Dyskinesia

A new drug valbenazine (trade name Ingrezza) has been approved by the US Food and Drug Administration for the treatment of tardive dyskinesia.

Tardive dyskinesia, a side effect of long-term use of antipsychotic medication, consists of involuntary movements of the tongue, face, torso, arms, and legs. It can interfere with walking, talking, and breathing.

The approval followed 20 clinical trials of valbenazine that included a total of more than 1000 participants who had symptoms of tardive dyskinesia in addition to schizophrenia, schizoaffective disorder, or bipolar disorder.

In a 2017 article in the American Journal of Psychiatry, researcher Robert A. Hauser and colleagues reported that patients who received 80 mg/day of valbenazine had a significant reduction in tardive dyskinesia symptoms after six weeks compared to those who received placebo. Participants who received 40 mg/day of valbenazine also had reductions in symptoms, although not as dramatic as with the higher dose.

Serious side effects of valbenazine include sleepiness and lengthening of the QT interval, which can increase heart arrhythmias. The FDA notes that people who already have abnormal heartbeats due to a long QT interval should not take valbenazine. In addition, people taking the drug should avoid driving or operating heavy machinery until they know how valbenazine affects them.

Article source: http://bipolarnews.org/?p=4202

Image:  Living in Stigma

2 thoughts on “Do you know what Tardive Dyskinesia is?

  1. updownflight says:

    That sounds like great news.

    I have never had TD, but had a very brief dystonia. I did see an elderly lady in the hospital with TD, and it was horrible. I would hope that in addition to this medication helping people who recently developed TD, it could also help the elderly lady I mentioned who has probably had it for many years.

    Liked by 1 person

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