Depression: Combo of antidepressants and painkillers risky

Science Daily, Jul 15/15 ~  Taking a combination of antidepressants and common painkillers is associated with an increased risk of bleeding soon after starting treatment, finds a new study. The researchers say their results may have been affected by other unmeasured or unknown factors and should be interpreted with caution. However, they suggest special attention is needed when patients use both these classes of drugs together.

The researchers say their results may have been affected by other unmeasured or unknown factors and should be interpreted with caution. However, they suggest special attention is needed when patients use both these classes of drugs together.

Depression produces the greatest decrement in health of all common chronic conditions and depression in older people is an important public health problem.

But concern exists that antidepressants may interact with common painkillers called non-steroidal anti-inflammatory drugs (NSAIDs) to increase the risk of bleeding inside the skull (intracranial haemorrhage).

So a team of researchers based in Korea compared the risk of bleeding among patients treated with antidepressants with and without NSAIDs.

Using the Korean nationwide health insurance database, their study involved over four million people who were prescribed antidepressants for the first time between 2009 and 2013.

NSAID prescriptions were obtained and hospital records were used to identify time to first admission with intracranial haemorrhage within 30 days of a new prescription. Factors that could affect the results, such as age, sex, and use of other medications, were taken into account.

Compared with use of antidepressants alone, the team found that combined use of antidepressants and NSAIDs was associated with a substantially increased bleeding risk.

More on this article @ http://www.sciencedaily.com/releases/2015/07/150714200049.htm

4 thoughts on “Depression: Combo of antidepressants and painkillers risky

  1. booguloo says:

    Come and get it… There must be a new way out of here said the joker to the thief. With normal consideration and history of nsaids I can understand. I personally can’t take nsaids and I’m happy about it. It’s like a hot poker in my stomach. I’ve been on antidepressants longer than some of you have been alive. It seems we could have seen this coming a lot sooner.

    Like

    • cherished79 says:

      True, even though I use Tylenol X-strength (also have costly prescription migraine meds), it just doesn’t cut it for week-long migraine. I’ve been on an anti-d for years also. Interesting article I thought.

      Like

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